Archives: 2019-07-25

A New Liquid Biopsy Chip Developed at Worcester Polytechnic institute Detects Circulating Tumor Cells in 100 Percent of Blood Samples from Stage 1-4 Breast Cancer Patients

Using the tendency of circulating cancer cells to adhere to carbon nanotubes, the easily mass-produced chip captures living cells and cell clusters of multiple types and sizes with high reliability and makes them available for analysis. The chip could be used to detect tumors at the earliest stages, before they can metastasize Researchers at Worcester

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To understand a childhood brain tumor, researchers turn to single-cell analysis

Research at St. Jude Children’s Research Hospital and Massachusetts General Hospital digs into the cells of origin for key medulloblastoma subtypes Investigators at St. Jude Children’s Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor. The work also has implications for how

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Global Innovation Index 2019: the future for medical innovation. RESTORE community topics at the tops

The World Intellectual Property Organization, WIPO, named Switzerland as the world’s most innovative country on Wednesday, during the launch of its latest Global Innovation Index, (GII) in the Indian capital New Delhi. Following Switzerland in the rankings are Sweden, the United States, the Netherlands and the United Kingdom. India has risen most in the rankings since

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CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity

A new kind of CAR-T becomes a micro-pharmacy, eliminating glioblastoma in mice n immunotherapy for cancer, the buzziest area of research is combinations: one checkpoint drug with another, say, or a checkpoint drug with chemotherapy. The latest brainstorm is an acronym lover’s dream team: CAR-Ts and BiTEs. In a mouse study reported on Monday in Nature Biotechnology, the

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Microfluidics device helps diagnose sepsis in minutes

When time matters in hospitals, automated system can detect an early biomarker for the potentially life-threatening condition. A novel sensor designed by MIT researchers could dramatically accelerate the process of diagnosing sepsis, a leading cause of death in U.S. hospitals that kills nearly 250,000 patients annually. Sepsis occurs when the body’s immune response to infection

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Position Statement from the German Biobank Alliance on the Cooperation Between Academic Biobanks and Industry Partners

Under the umbrella of the German Biobank Node (GBN), 11 biobanks and two IT development centers are funded by the Federal Ministry of Education and Research (BMBF) to work together in the German Biobank Alliance (GBA). Their common aim is to make existing biomaterials hosted by different biobanks nationally and internationally available for biomedical research.

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The Landscape of Cellular and Gene Therapy Products: Authorization, Discontinuations, and Cost

Source Human Gene Therapy Clinical Development Background: Cell and gene therapy products belong to a diverse class of biopharmaceuticals known as advanced therapy medicinal products. Cell and gene therapy products are used for the treatment and prevention of diseases that until recently were only managed chronically. The objective of this study was to examine the characteristics

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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

Researchers at the University of Calgary have discovered a previously unidentified cell population with the power to heal injured hearts. The cells were found in the pericardial fluid inside the sac around the heart.  Gata6+ pericardial cavity macrophage The study was led by Drs. Paul Kubes, PhD, Justin Deniset, PhD and Paul Fedak, MD, PhD. The specific

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