Amgen has showcased some encouraging early stage data from candidates based on its novel bispecific T cell engager (BiTE) platform at ASCO. Bispecific antibodies are one of the most promising emerging areas in immuno-oncology, with numerous biotechs and pharma companies developing their own variants of the technology. The potential is for the treatments to show
In ‘Differential thermal analysis of the antibacterial effect of PLA-based materials planned for 3D printing,’ authors P. Maroti, B. Kocsis, A. Ferencz, M. Nyitrai, and D. Lorinczy explore the opportunities biomedical applications offer to research and medicine, along with the importance of evaluating materials used in creating devices. In this study, researchers are specifically concerned
In research published this week, scientists have found that a therapy originally developed to treat Alzheimer’s Disease could hold promise for children with T-cell acute lymphoblastic leukaemia. An international team of researchers at VIB-KU Leuven, Belgium, the UK Dementia Institute and Children’s Cancer Institute, Australia, have identified a novel therapy for T-cell acute lymphoblastic leukaemia
On a mission to improve robotics, researchers have developed a sensor-packed glove that can learn the signatures of the human grasp. The sensor will help the neural network to identify objects by touch. The aim of the development, which comes from the Massachusetts Institute of Technology, is to pinpoint the signals that can help a neural
Source The Guardian International Life Sciences Institute used by corporate backers to counter public health policies, says study An institute whose experts have occupied key positions on EU and UN regulatory panels is, in reality, an industry lobby group that masquerades as a scientific health charity, according to a peer-reviewed study. The Washington-based International Life Sciences
This article discusses the scope and purpose of the special designation for Regenerative Medicine Advanced Therapies (RMAT) created by the passage of the 21st Century Cures Act. The authors explain the benefits expected to be realized with RMAT, such as keeping the US globally competitive in the field. They provide a tally of products receiving the special
Article Highlights CAR T-cell therapy is gaining traction in relapsed/refractory lymphoma in older patients with aggressive disease. As a result of prospective trials investigating CAR T-cell therapy, there is potential that older patients with lymphoma can be spared multiple lines of chemotherapy and its resultant toxicities while still having long-term clinical benefit. Toxicities are still
The international, randomised phase III MONALEESA-7 trial found that adding ribociclib to standard-of-care endocrine therapy significantly improved overall survival for premenopausal women with advanced HR-positive/HER2-negative breast cancer compared with endocrine therapy alone. After 42 months of follow-up, the survival rate was 70% for women who took the combination therapy compared with 46% for women who
Study finds engaging young children in conversation is more important for brain development than “dumping words” on them. A landmark 1995 study found that children from higher-income families hear about 30 million more words during their first three years of life than children from lower-income families. This “30-million-word gap” correlates with significant differences in tests
Just over a year after Roche and GE joined forces to develop clinical decision tools to help guide treatment, the duo have announced their first product. The result is a clinical ‘dashboard’ – called NAVIFY Tumour Board 2.0 – which brings together data from diagnostic tests and medical imaging into one place, and according to
