Source NIH The blood-brain barrier, or BBB, is a dense sheet of cells that surrounds most of the brain’s blood vessels. The BBB’s tiny gaps let vital small molecules, such as oxygen and water, diffuse from the bloodstream into the brain while helping to keep out larger, impermeable foreign substances that don’t belong there. But
Orgenesis, a developer, manufacturer and service provider of advanced cell therapies, announced that the United States Food & Drug Administration (“FDA”) has granted Orphan Drug designation for its Autologous Insulin Producing (“AIP”) cells as a cell replacement therapy for the treatment of severe hypoglycemia-prone diabetes resulting from total pancreatectomy (“TP”) due to chronic pancreatitis (“CP”).
Two recent studies highlight novel ways to combat pattern hair loss in men and women using small molecules such as JAK inhibitors that reawaken dormant hair follicles, as well as stem cell therapies aimed at growing new follicles. In the first study, researchers led by Angela Christiano, PhD, the Richard & Mildred Rhodebeck Professor of Dermatology at
Experiments in mice show transmission of nerve-killing protein from the gut into the brain In experiments in mice, Johns Hopkins Medicine researchers say they have found additional evidence that Parkinson’s disease originates among cells in the gut and travels up the body’s neurons to the brain. The study, described in the June issue of the
A robotic glove powered by 5G could help diagnose patients still on their way to hospital in a UK first. University Hospitals Birmingham NHS Foundation Trust (UHB), BT and WM5G have teamed up to deliver new technologies for front-line staff to diagnose patients quicker, including enabling remote diagnostics performed by paramedics. 5G capabilities would allow
Tendon tissues have limited healing capacity. The incidence of tendon injuries and the unsatisfactory functional outcomes of tendon repair are driving the search for alternative therapeutic approaches envisioning tendon regeneration. Cellular therapies aim at delivering adequate, regeneration-competent cell types to the injured tendon and toward ultimately promoting its reconstruction and recovery of functionality. Mesenchymal stem
At U.S. clinics advertising unproven stem cell treatments, roughly two-thirds of the clinicians may be physicians, but a new study suggests these doctors are often trained in specialties unrelated to the services they provide. “About half of the companies we examined offer unproven stem cell treatments for conditions (for) which they do not have a
Source NIH Scientists continue to uncover the many fascinating ways in which the trillions of microbes that inhabit the human body influence our health. Now comes yet another surprising discovery: a medicine-eating bacterium residing in the human gut that may affect how well someone responds to the most commonly prescribed drug for Parkinson’s disease. There
In ‘Application of high resolution DLP stereolithography for fabrication of tricalcium phosphate scaffolds for bone regeneration,’ researchers examine how to make complex, stable scaffolds based on β-tricalcium. Typically, there are obstacles to finding materials and techniques suitable for creating structures capable of sustaining cell life. Here, the authors are aware of the necessities in tissue
This paper on Trends in Cell Biology has been yesterday by Research Group on Stem Cell Aging, Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), Beutenbergstr. 11, 07745 Jena, Germany with the following highlights: The quiescence stage of stem cells has beneficial and adverse effects on stem cell aging. Stem cell quiescence delays stem
