March 2019 – Page 2 – REGENHEALTHSOLUTIONS (RHS)

PIER MARIA FORNASARI
2019-03-25

A special edition of The American Statistician presents over 40 papers on “Statistical inference in the 21st century: a world beyond P < 0.05”

Statistical significance has become an infallible doctrine of scientific research. However, many scientists and statisticians argue that long-held beliefs about statistical significance have, in fact, harmed the scientific community. In hypothesis testing, the p-value gives the probability or likelihood that the null hypothesis is true and is frequently used as a measure of “statistical significance.”

No Comments InREGENERATIVE MEDICINE

PIER MARIA FORNASARI
2019-03-22

A New Role for Platelets: Boosting Neurogenesis After Exercise

A mouse study finds that when blood platelets are activated during exercise, they release factors that increase the number of newborn neurons in the hippocampus. It’s well established that exercise is good for the mammalian brain. As early as 1999, researchers discovered considerably more newborn neurons in the hippocampi of mice that had access to

One comment InREGENERATIVE MEDICINE

PIER MARIA FORNASARI
2019-03-21

Hope for people with FOP disease as three drugs enter clinical trial – and one could be approved by next year

Fibrodysplasia ossificans progressiva (FOP) is a rare, genetic disease in which damaged muscle and soft tissue turn into bone It affects just 800 people worldwide and there is currently no known cure Three drugs have entered clinical trials as potential treatments for the condition They target the genes and proteins responsible for the hyperactive bone growth

No Comments InGENE THERAPY RARE DISEASES

PIER MARIA FORNASARI
2019-03-21

Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality

Question Is consuming dietary cholesterol or eggs associated with incident cardiovascular disease (CVD) and all-cause mortality? Findings Among 29 615 adults pooled from 6 prospective cohort studies in the United States with a median follow-up of 17.5 years, each additional 300 mg of dietary cholesterol consumed per day was significantly associated with higher risk of incident CVD (adjusted

No Comments InWELLNESS

PIER MARIA FORNASARI
2019-03-19

‘Real World’ Data on Costs With CAR-T Cell Therapy

The formidable price tag of the new chimeric antigen receptor (CAR) T-cell therapies has sent shock waves through the blood cancers community, which is struggling to incorporate this novel approach because of the remarkable responses that have been seen. But the price tags — enormous as they are (nearly half a million [$475,000] for tisagenlecleucel [Kymriah, Novartis]

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PIER MARIA FORNASARI
2019-03-19

US FDA approves the first immunotherapy for extensive-stage small cell lung cancer

Tecentriq in combination with chemotherapy (carboplatin and etoposide) is the first and only cancer immunotherapy approved for the initial treatment of extensive-stage small cell lung cancer (ES-SCLC) First new initial treatment option approved by the U.S. Food and Drug Administration (FDA) for people with ES-SCLC in more than 20 years Tecentriq in combination with chemotherapy

No Comments InIMMUNOTHERAPY

PIER MARIA FORNASARI
2019-03-19

Researchers predict 1.4 million deaths from all cancers in 2019 in the EU

Overall death rates from breast cancer fall in the EU, but rise in Poland Death rates from breast cancer are predicted to fall in all European Union (EU) countries in 2019 with the exception of Poland, according to new research published in the leading cancer journal Annals of Oncology In their annual predictions for cancer deaths

No Comments InWELLNESS

PIER MARIA FORNASARI
2019-03-19

Experimental blood test accurately spots fibromyalgia

Study finds unique ‘molecular signature’ for often-misdiagnosed disease For the first time, researchers have evidence that fibromyalgia can be reliably detected in blood samples – work they hope will pave the way for a simple, fast diagnosis. In a study that appears in the Journal of Biological Chemistry, researchers from The Ohio State University report success in

No Comments InWELLNESS

PIER MARIA FORNASARI
2019-03-19

The genetics of regeneration

Study uncovers genes that control process of whole-body regeneration A new study looks at how three-banded panther worms are able to regenerate their whole bodies and how this regeneration could be applied to humans. Video by Yi-Jyun Luo When it comes to regeneration, some animals are capable of amazing feats. If you cut off a

No Comments InREGENERATIVE MEDICINE

PIER MARIA FORNASARI
2019-03-18

With single gene insertion, blind mice regain sight

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems. They were able to see motion, brightness changes over a thousandfold range and fine detail on

One comment InGENE THERAPY RARE DISEASES

REGENERATIVE AND PERSONALISED MEDICINE

DIGITAL HEALTHCARE

Archives: 2019-03-25

A special edition of The American Statistician presents over 40 papers on “Statistical inference in the 21st century: a world beyond P < 0.05”

A New Role for Platelets: Boosting Neurogenesis After Exercise

Hope for people with FOP disease as three drugs enter clinical trial – and one could be approved by next year

Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality

‘Real World’ Data on Costs With CAR-T Cell Therapy

US FDA approves the first immunotherapy for extensive-stage small cell lung cancer

Researchers predict 1.4 million deaths from all cancers in 2019 in the EU

Experimental blood test accurately spots fibromyalgia

The genetics of regeneration

With single gene insertion, blind mice regain sight